Abstract: This paper studied the differences in liposoluble and water-soluble constituents in Salvia miltiorrhiza Bge.and S.miltiorrhiza Bge.f.alba collected at different growth stages and areas.The equation model was used to analyze the accumulative process of active constituents with growth stage.The research determined theories for cultivation and quality control in S.miltiorrhiza.Results showed that the liposoluble content in S.miltiorrhiza bge.f. alba had two maximums values at the end of July and October, respectively, while the liposoluble content in S.miltiorrhiza Bge.reached a maximum value at the end of July.The water-soluble contents in S.miltiorrhiza Bge.and S.miltiorrhiza Bge.f.alba reached maximum values in June to July.The contents of active constituents in S.miltiorrhiza Bge.f. alba were higher than those in S.miltiorrhiza Bge.cultivated for two years.Content of rosmarinic acid aboveground was higher than that in the root in both S.miltiorrhiza.The content of salvianolic acid B in the roots was simulated with the first-order equation Y=-8.105X+81.047 and Y=-13.777X+117.917, respectively.The content of salvianolic acid B decreased with the growth of plants.